Her big-screen debut was in the thriller TAG: The Assassination Game (1982) and as a result, she was listed as one of twelve "Promising New Actors of 1982" in John Willis' Screen World, Vol. She also shared a starring role in the CBS made-for-TV movie Country Gold, with Loni Anderson and Earl Holliman.Hamilton played the lead role in Children of the Corn, based on the horror short story by Stephen King.The movie, which made million at the box office, Following The Terminator, Hamilton starred in Black Moon Rising, an action thriller with Tommy Lee Jones.
Following the success of the Terminator series, she hosted Saturday Night Live.
In New York, she attended acting workshops given by Lee Strasberg.
Hamilton's acting debut came first on television, followed by a major role as Lisa Rogers in the prime-time soap opera Secrets of Midland Heights (December 1980/January 1981).
Hamilton underwent intense physical training to emphasize the character's transformation from the first film.
Her identical twin sister was Linda's double in Terminator 2.